List of Senators who served with Muskie, by name
Key: C – Conservative; D – Democrat; R – Republican
| Abourezk, James G. | D | 1973-1979 | South Dakota |
| Aiken, George David | R | 1941-1975 | Vermont |
| Allen, James Browning | D | 1969-1978 | Alabama |
| Allen, Maryon Pittman | D | 1978 | Alabama |
| Allott, Gordon Llewellyn | R | 1955-1973 | Colorado |
| Anderson, Clinton Presba | D | 1949-1973 | New Mexico |
| Anderson, Wendell R. | D | 1976-1978 | Minnesota |
| Armstrong, William L. | R | 1979-1991 | Colorado |
| Baker, Howard H., Jr. | R | 1967-1985 | Tennessee |
| Bartlett, Dewey Follett | R | 1973-1979 | Oklahoma |
| Bartlett, Edward Lewis (Bob) | D | 1959-1968 | Alaska |
| Bass, Ross | D | 1964-1967 | Tennessee |
| Baucus, Max Sieben | D | 1978 – present | Montana |
| Bayh, Birch | D | 1963-1981 | Indiana |
| Beall, James Glenn | R | 1953-1965 | Maryland |
| Beall, James Glenn, Jr. | R | 1971-1977 | Maryland |
| Bellmon, Henry L. | R | 1969-1981 | Oklahoma |
| Bennett, Wallace Foster | R | 1951-1974 | Utah |
| Bentsen, Lloyd M., Jr. | D | 1971 – January 20, 1993 | Texas |
| Bible, Alan H. | D | 1954-1974 | Nevada |
| Biden, Joseph R. | D | 1973 – present | Delaware |
| Blakeley, William A. | D | 1961-1961 | Texas |
| Boggs, J. Caleb | R | 1961-1973 | Delaware |
| Boren, David Lyle | D | 1979 – November 15, 1994 | Oklahoma |
| Boschwitz, Rudy | R | 1978-1991 | Minnesota |
| Bottum, Joseph H. | R | 1962-1963 | South Dakota |
| Bradley, William Warren (Bill) | D | 1979-1997 | New Jersey |
| Brewster, Daniel B. | D | 1963-1969 | Maryland |
| Bridges, Henry Styles | R | 1937-1961 | New Hampshire |
| Brock, William E., III | R | 1971-1977 | Tennessee |
| Brooke, Edward W. | R | 1967-1979 | Maryland |
| Brunsdale, Clarence Norman | R | 1959-1960 | North Dakota |
| Buckley, James L. | C | 1971-1977 | New York |
| Bumpers, Dale | D | 1975-1999 | Arkansas |
| Burdick, Quentin Northrup | D | 1960 – September 8, 1992 | North Dakota |
| Bush, Prescott Sheldon | R | 1952-1963 | Connecticut |
| Butler, John Marshall | R | 1951-1963 | Maryland |
| Byrd, Harry Flood, Sr. | D | 1933-1965 | Virginia |
| Byrd, Harry Flood, Jr. | D | 1965-1983 | Virginia |
| Byrd, Robert Carlyle | D | 1959 – present | West Virginia |
| Cannon, Howard Walter | D | 1959-1983 | Nevada |
| Capehart, Homer Earl | R | 1945-1963 | Indiana |
| Carlson, Frank | R | 1950-1969 | Kansas |
| Carroll, John Albert | D | 1957-1963 | Colorado |
| Case, Clifford Phllip | R | 1955-1979 | New Jersey |
| Case, Francis Higbee | R | 1951-1962 | South Dakota |
| Chafee, John Hubbard | R | 1976-2001 | Rhode Island |
| Chavez, Dennis | D | 1935-1962 | New Mexico |
| Chiles, Lawton M., Jr. | D | 1971-1989 | Florida |
| Church, Frank Forrester | D | 1957-1981 | Idaho |
| Clark, Dick | D | 1973-1979 | Iowa |
| Clark, Joseph Sill | D | 1957-1969 | Pennsylvania |
| Cochran, William Thad | R | 1978 – present | Mississippi |
| Cohen, William S. | R | 1979-1997 | Maine |
| Cook, Marlow W.W. | R | 1968-1974 | Kentucky |
| Cooper, John Sherman | R | 1946-1949, 1952-1973 | Kentucky |
| Cotton, Norris | R | 1954-1974, 1975-1975 | New Hampshire |
| Cranston, Alan | D | 1969-1993 | California |
| Culver, John C. | D | 1975-1981 | Iowa |
| Curtis, Carl Thomas | R | 1955-1979 | Nebraska |
| Danforth, John C. | R | 1976-1995 | Missouri |
| DeConcini, Dennis | D | 1977-1995 | Arizona |
| Dirksen, Everett McKinley | R | 1951-1969 | Illinois |
| Dodd, Thomas Joseph | D | 1959-1971 | Connecticut |
| Dole, Robert J. | R | 1969 – June 11, 1996 | Kansas |
| Domenici, Pete Vichi | R | 1973 – present | New Mexico |
| Dominick, Peter H. | R | 1963-1975 | Colorado |
| Douglas, Paul Howard | D | 1949-1967 | Illinois |
| Durenberger, David | R | 1978-1995 | Minnesota |
| Durkin, John A. | D | 1975 – December 29, 1980 | New Hampshire |
| Dworshak, Henry Clarence | R | 1946-1962 | Idaho |
| Eagleton, Thomas F. | D | 1968-1987 | Missouri |
| Eastland, James Oliver | D | 1941-1941, 1943-1978 | Mississippi |
| Edmondson, J. Howard | D | 1963-1964 | Oklahoma |
| Edwards, Elaine | D | 1972-1972 | Louisiana |
| Ellender, Allen Joseph | D | 1937-1972 | Louisiana |
| Engle, Clair | R | 1959-1964 | California |
| Ervin, Samuel J., Jr. | D | 1954-1974 | North Carolina |
| Exon, J. James | D | 1979-1997 | Nebraska |
| Fannin, Paul Jones | R | 1965-1977 | Arizona |
| Fong, Hiram Leong | R | 1959-1977 | Hawaii |
| Ford, Wendell H. | D | 1974-1999 | Kentucky |
| Frear, Joseph Allen, Jr. | D | 1949-1961 | Delaware |
| Fulbright, J. William | D | 1945-1974 | Arkansas |
| Gambrell, David H. | D | 1971-1972 | Georgia |
| Garn, E.J. (Jake) | R | 1974-1993 | Utah |
| Glenn, John Herschel, Jr. | D | 1974-1999 | Ohio |
| Goldwater, Barry Morris | R | 1953-1965, 1969-1987 | Arizona |
| Goodell, Charles E. | R | 1968-1971 | New York |
| Gore, Albert Arnold | D | 1953-1971 | Tennessee |
| Gravel, Maurice R. (Mike) | D | 1969-1981 | Alaska |
| Green, Theodore Francis | D | 1937-1961 | Rhode Island |
| Griffin, Robert P. | R | 1966-1979 | Michigan |
| Gruening, Ernest | D | 1959-1969 | Alaska |
| Gurney, Edward J. | R | 1969-1974 | Florida |
| Hansen, Clifford P. | R | 1967-1978 | Wyoming |
| Hatfield, Paul G. | D | 1978-1978 | Montana |
| Harris, Fred R. | D | 1964-1973 | Oklahoma |
| Hart, Gary | D | 1975-1987 | Colorado |
| Hart, Philip Aloysius | D | 1959-1976 | Michigan |
| Hartke, Rupert Vance | D | 1959-1977 | Indiana |
| Haskell, Floyd K. | D | 1973-1979 | Colorado |
| Hatch, Orrin G. | R | 1977 – present | Utah |
| Hatfield, Mark O. | R | 1967-1997 | Oregon |
| Hathaway, William D. | D | 1973-1979 | Maine |
| Hayakawa, S.I. | R | 1977-1983 | California |
| Hayden, Carl Turnbull | D | 1927-1969 | Arizona |
| Heflin, Howell Thomas | D | 1979-1997 | Alabama |
| Heinz, H. John, III | R | 1977 – April 4, 1991 | Pennsylvania |
| Helms, Jesse | R | 1973-2003 | North Carolina |
| Hennings, Thomas Carey, Jr. | D | 1951-1960 | Missouri |
| Hickenlopper, Bourke Blakemore | R | 1945-1969 | Iowa |
| Hickey, J.J. | D | 1961-1962 | Wyoming |
| Hill, Joseph Lister | D | 1938-1969 | Alabama |
| Hodges, Kaneaster, Jr. | D | 1977-1979 | Arkansas |
| Holland, Spessard Lindsey | D | 1946-1971 | Florida |
| Hollings, Ernest S. | D | 1966 – present | South Carolina |
| Hruska, Roman Lee | R | 1954-1976 | Nebraska |
| Huddleston, Walter (Dee) | D | 1973-1985 | Kentucky |
| Hughes, Harold E. | D | 1969-1975 | Iowa |
| Humphrey, Gordon J. | R | 1979 – December 4, 1990 | New Hampshire |
| Humphrey, Hubert Horatio, Jr. | D | 1949-1964, 1971-1978 | Minnesota |
| Humphrey, Muriel | D | 1978-1978 | Minnesota |
| Inouye, Daniel Ken | D | 1963 – present | Hawaii |
| Jackson, Henry Martin (Scoop) | D | 1953-1983 | Washington |
| Javits, Jacob Koppel | R | 1957-1981 | New York |
| Jepsen, Roger W. | R | 1979-1985 | Iowa |
| Johnson, Lyndon Baines | D | 1949-1961 | Texas |
| Johnston, J. Bennett, Jr. | D | 1972-1997 | Louisiana |
| Johnston, Olin DeWitt Talmadge | D | 1945-1965 | South Carolina |
| Jordan, Benjamin Everett | D | 1958-1973 | North Carolina |
| Jordan, Len B. | R | 1962-1973 | Idaho |
| Kassebaum, Nancy L. | R | 1979-1997 | Kansas |
| Keating, Kenneth Bernard | R | 1959-1965 | New York |
| Kefauver, Carey Estes | D | 1949-1963 | Tennessee |
| Kennedy, Edward M. | D | 1962 – present | Massachusetts |
| Kennedy, John Fitzgerald | D | 1953-1960 | Massachusetts |
| Kennedy, Robert Fitzgerald | D | 1965-1968 | New York |
| Kerr, Robert Samuel | D | 1949-1963 | Oklahoma |
| Kuchel, Thomas Henry | R | 1953-1969 | California |
| Langer, William | R | 1941-1959 | North Dakota |
| Lausche, Frank J. | D | 1957-1969 | Ohio |
| Laxalt, Paul | R | 1974-1987 | Nevada |
| Leahy, Patrick J. | D | 1975 – present | Vermont |
| Levin, Carl | D | 1979 – present | Michigan |
| Long, Edward Vaughn | D | 1960-1968 | Missouri |
| Long, Oren Ethelbert | D | 1959-1963 | Hawaii |
| Long, Russell Billin | D | 1949-1987 | Louisiana |
| Lugar, Richard G. | R | 1977 – present | Indiana |
| Lusk, Hall Stoner | D | 1960-1961 | Oregon |
| McCarthy, Eugene Joseph | D | 1959-1971 | Minnesota |
| McClellan, John Little | D | 1943-1977 | Arkansas |
| McClure, James A. | R | 1973-1991 | Idaho |
| McGee, Gale William | D | 1959-1977 | Wyoming |
| McGovern, George S. | D | 1963-1981 | South Dakota |
| McIntyre, Thomas J. | D | 1962-1979 | New Hampshire |
| McNamara, Patrick Vincent | D | 1955-1966 | Michigan |
| Magnuson, Warren Grant | D | 1945-1981 | Washington |
| Mansfield, Michael Joseph (Mike) | D | 1953-1977 | Montana |
| Martin, Thomas Ellsworth | R | 1955-1961 | Iowa |
| Mathias, Charles McC., Jr. | R | 1969-1987 | Maryland |
| Matsunaga, Spark M. | D | 1977-1990 | Hawaii |
| Mechem, Edwin L. | D | 1962-1964 | New Mexico |
| Melcher, John | D | 1977-1989 | Montana |
| Metcalf, Lee | D | 1961-1978 | Montana |
| Metzenbaum, Howard M. | D | 1974-1974, 1976-1995 | Ohio |
| Miller, Jack R. | R | 1961-1973 | Iowa |
| Mondale, Walter F. | D | 1964-1976 | Minnesota |
| Monroney, Almer Stillwell Mike | D | 1951-1969 | Oklahoma |
| Montoya, Joseph Manuel | D | 1964-1977 | New Mexico |
| Morgan, Robert B. | D | 1975-1981 | North Carolina |
| Morse, Wayne Lyman | D | 1945-1969 | Oregon |
| Morton, Thruston Ballard | R | 1957-1968 | Kentucky |
| Moss, Frank Edward | D | 1959-1977 | Utah |
| Moynihan, Daniel Patrick | D | 1977-2001 | New York |
| Mundt, Karl Earl | R | 1948-1973 | South Dakota |
| Murphy, George L. | R | 1965-1971 | California |
| Murphy, Maurice J., Jr. | R | 1961-1962 | New Hampshire |
| Murray, James Edward | D | 1935-1961 | Montana |
| Muskie, Edmund Sixtus | D | 1959 – May 7, 1980 | Maine |
| Nelson, Gaylord | D | 1963-1981 | Wisconsin |
| Neuberger, Maurine Brown | D | 1960-1967 | Oregon |
| Neuberger, Richard Lewis | D | 1955-1960 | Oregon |
| Nunn, Samuel A. | D | 1972-1997 | Georgia |
| O’Mahoney, Joseph Christopher | D | 1934-1953, 1954-1961 | Wyoming |
| Packwood, Robert W. | R | 1969 – October 1, 1995 | Oregon |
| Pastore, John Orlando | D | 1950-1976 | Rhode Island |
| Pearson, James B. | R | 1962-1978 | Kansas |
| Pell, Claiborne | R | 1961-1997 | Rhode Island |
| Percy, Charles H. | R | 1967-1985 | Illinois |
| Pressler, Larry Lee | R | 1979-1997 | South Dakota |
| Prouty, Winston Lewis | R | 1959-1971 | Vermont |
| Proxmire, William | D | 1957-1989 | Wisconsin |
| Pryor, David H. | D | 1979-1997 | Arkansas |
| Randolph, Jennings | D | 1959-1985 | West Virginia |
| Ribicoff, Abraham A. | D | 1963-1981 | Connecticut |
| Riegle, Donald W., Jr. | D | 1976-1995 | Michigan |
| Robertson, Absalom Willis | D | 1947-1966 | Virginia |
| Roth, William Victor, Jr. | R | 1971-2001 | Delaware |
| Russell, Donald S. | D | 1965-1966 | South Carolina |
| Russell, Richard Brevard, Jr. | D | 1933-1971 | Georgia |
| Salinger, Pierre | D | 1964-1964 | California |
| Saltonstall, Leverett | R | 1945-1967 | Massachusetts |
| Sarbanes, Paul S. | D | 1977 – present | Maryland |
| Sasser, James R. | D | 1977-1995 | Tennessee |
| Saxbe, William B. | R | 1969-1974 | Ohio |
| Schmitt, Harrison H. | R | 1977-1983 | New Mexico |
| Schoeppel, Andrew Frank | R | 1949-1962 | Kansas |
| Schweiker, Richard S. | R | 1969-1981 | Pennsylvania |
| Scott, Hugh Doggett, Jr. | R | 1959-1977 | Pennsylvania |
| Scott, William L. | R | 1973-1979 | Virginia |
| Simpson, Alan K. | R | 1979-1997 | Wyoming |
| Simpson, Milward L. | R | 1962-1967 | Wyoming |
| Smathers, George Armistead | D | 1951-1969 | Florida |
| Smith, Benjamin A.H., II | D | 1960-1962 | Massachusetts |
| Smith, Margaret Chase | R | 1949-1973 | Maine |
| Smith, Ralph T. | R | 1969-1970 | Illinois |
| Sparkman, John Jackson | D | 1946-1979 | Alabama |
| Spong, William B., Jr. | D | 1966-1973 | Virginia |
| Stafford, Robert T. | R | 1971-1989 | Vermont |
| Stennis, John Cornelius | D | 1947-1989 | Mississippi |
| Stevens, Theodore F. | R | 1968 – present | Alaska |
| Stevenson, Adlai E., III | D | 1970-1981 | Illinois |
| Stewart, Donald W. | D | 1978-1981 | Alabama |
| Stone, Richard B. | D | 1975 – December 30, 1981 | Florida |
| Symington, William (Stuart) | D | 1953-1976 | Missouri |
| Taft, Robert, Jr. | R | 1971-1976 | Ohio |
| Talmadge, Herman Eugene | D | 1957-1981 | Georgia |
| Thurmond, James Strom | D/R | 1954-2003 | South Carolina |
| Tower, John G. | R | 1961-1985 | Texas |
| Tsongas, Paul | D | 1979-1985 | Massachusetts |
| Tunney, John V. | D | 1971-1977 | California |
| Tydings, Joseph D. | D | 1965-1971 | Maryland |
| Wallop, Malcolm | R | 1977-1995 | Wyoming |
| Walters, Herbert S. | D | 1963-1964 | Tennessee |
| Warner, John W. | R | 1979 – present | Virginia |
| Weicker, Lowell P. | R | 1971-1995 | Connecticut |
| Wiley, Alexander | R | 1939-1963 | Wisconsin |
| Williams, Harrison A., Jr. | D | 1959-1982 | New Jersey |
| Williams, John James | R | 1947-1970 | Delaware |
| Wyman, Louis Crosby | R | 1974-1975 | New Hampshire |
| Yarborough, Ralph Webster | D | 1957-1971 | Texas |
| Young, Milton Ruben | R | 1945-1981 | North Dakota |
| Young, Stephen M. | D | 1959-1971 | Ohio |
| Zorinsky, Edward | D | 1976-1987 | Nebraska |