Lecturer, Assistant in Instruction

Associations
Biology Department

Dana Hall, Room 322

About

I am a Maine native, and grew up on a rural farm in the western mountains. I originally attended culinary arts school and after years of working in the food service industry, I decided to pursue my original interest – biology. I study how aging changes the brain and how those changes can predispose some people to develop neurological diseases such as Parkinson’s disease or Alzheimer’s disease. I use a wide variety of techniques to explore how some people’s protective genes are turned off during aging, and identified a new type of cell in the brain that only shows up in people at risk for neurological diseases. I also study how we (humans) affect the world around us and how some of the smallest organisms like bacteria can change in response to the things we put into our world. I’m epecially interested in agriculture and how PFAS contamination in Maine that was hidden in organic fertilizers has changed the biology of the soils and plants that grow in it. I teach laboratory techniques, advanced biological research, and scientific writing.

A Selection of Relevant Prior Work
  • Publication: Adams L, Song MS, Tanaka Y, Kim YS. A single-nuclei paired multiomic analysis of the human midbrain reveals age- and Parkinson’s disease-associated glial changes. Nature Aging 2024, In Press.
  • Publication: Adams L, Guhathakurta S, , Jeong I, Sivakumar A*, Cha M*, Bernardo Fiadeiro M*, Hu HN, Kim YS. Precise epigenomic editing with a SunTag-based modular epigenetic toolkit. Epigenetics. 2022 Aug 3:1-7. doi: 10.1080/15592294.2022.2106646
  • Publication: Song MK, Adams L, Lee JH, Kim YS. NXP031 prevents dopaminergic neuronal loss and oxidative damage in the AAV-WT-α-synuclein mouse model of Parkinson’s disease. PLoS One. 2022 Jul 28;17(7):e0272085. doi: 10.1371/journal.pone.0272085.
  • Publication: Guhathakurta S, Kim J, Adams L, Basu S, Song MK, Adler E*, Je G, Fiadeiro MB*, Kim YS. Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s disease. EMBO Mol Med. 2021 Feb 5;13(2):e12188. doi: 10.15252/emmm.202012188.